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PRODUCT INFORMATION

Prodrin Features triple active headache relief

Isometheptene

A vasoconstrictor which acts on dilated cranial and cerebral arterioles with action similar to ergotamine but where ergotamine is not permitted.  


Caffeine

A stimulant, given with headache formulations to increase their effectiveness and prevent sedation.


Acetaminophen

An effective non-narcotic analgesic, which reduces the perception of pain impulses originating from dilated cerebral vessels.  

Hepatotoxicity

Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death.  Most of the cases of liver injury are assocatied with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen containing product.